No. 61
in skincare
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How it works.
71% would recommend
Why we ranked it No. 61 in skincare
Sample
47 redditors with explicit opinion · 10 positive · 2 negative · 2 neutral
Score0.744 — formula: 0.75 × % positive + 0.25 × pos/neg ratio
Confidence95% CI: 45–88% · the true approval rate falls in this range with 95% statistical confidence
Verdict
Reddit Confirmed — Threshold-based label from our methodology.
Sources
r/koreanskincare, r/tretinoin, r/KoreanBeauty
Medicube · skincare
Reddit Confirmed
Medicube pdrn serum
r/koreanskincarer/tretinoinr/KoreanBeauty
TL;DR — Reddit consensus
The most-discussed accessible PDRN (salmon DNA) serum of the 2026 trend. Users report plumper, calmer skin; evidence base still young.
COMPARE WITH
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Direct quotes
What 44 redditors actually said.
Top 5 by confidence shown — expand below for the rest. Click any to open the original on Reddit.
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u/Character-Corner5311
·
r/koreanskincare
area with spicule products, as the skin there is quite thin and might get irritated by the micro-needles. **Medicube PDRN Serum** Personally, this was the most disappointing product from this purchase. I had high expectations, but it feels a bit sticky after application and not a
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u/Organic_Pattern1856
·
r/koreanskincare
and Reviews Skin type: Dry and sensitive Skin concerns: Hyperpigmentation, anti aging, acne prevention Medicube rose PDRN serum (4/10) Scent: Rose Texture: watery serum Product claims: anti aging, dryness, dullness, dark spots, uneven skin tone, loss of firmness/elasticity Result
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u/spicywisdom
·
r/KoreanBeauty
mature skin. I tried Anua serums (the red one and the green one). They left my skin quite sticky. I tried Medicube Pore products, Mediheal PDRN toner pads, Jiyu pads (they work pretty well), and CeraVe Foaming Cleanser. I was all over the place. As I was going on a trip and liked
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u/Swedishgirl_1996
·
r/tretinoin
wash with water or oil cleanser, Finacea 15%, medicube PDRN serum, ACO face day
S
u/Swedishgirl_1996
·
r/tretinoin
wash with water or oil cleanser, Finacea 15%, medicube PDRN serum, ACO face day
Show all 44 mentions ↓
"I see an improvement! Coupled with extra hours of sleep. Do you apply eye cream on your upper eyelids? How close to the lash line if so? Thanks! Excuse my brows please. **Update**: I used up the whole tube. I feel it …"
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"recommend for oily skin with visible pores? Also, the Centella serum didn't show much difference, and the Medicube PDRN didn't do much for my under-eye bags"
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"a week and slowly increase as your skin builds tolerance. If you're looking for serums, I'd recommend the PDRN Pink Peptide Serum from Medicube and the Seoul 1988 serum retinal liposome 2% + black ginseng from K-Secret!!"
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"PM. Moisturizer: **dr g blemish calming soothing cream** or **torriden balanceful cream** If you ever want pdrn collagen products, Medicube, Biodance, VT cosmetics and Round Labs have a great line. Sunblock: **skin 10…"
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"I use Medicube pink pdrn serum. Very hydrating."
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"avaliable in the US but the purito centella products r really good for calming the skin, i pair it with medicube pink pdrn serum and that helps a lot with brigntness and scaring"
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"if you can’t afford it right now Also a PDRN clean is good with it I will suggest you to get the VT pdrn cream instead of the medicube one as it worked much better for me"
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"and repair. I heard vitamin C is best used in the mornings though. Personally I pair vitamin c with pdrn at different times.. Medicube has some great stuff. I love their PDRN gel pads. I use them at night bc you shoul…"
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"I find Medicube pink serum to be very hydrating and soothing."
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"you need the tiniest amount 3) a serum or serum oil- there are so many out there. I do personally love the Medicube PDRN Pink Collagen, I also use Acure Brightening Glow Serum. I use both together in that order, every…"
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"I've started using the Medicube PDRN Lip Sleeping Mask at night and then Torriden SOLID IN Ceramide Lip Essence during the day before going out in the morning and I'll apply an SPF lip balm during the day to maintain …"
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"from that line is unbeatable. It’s by far the best SPF I’ve used. You don’t even need moisturizer under it. Medicube has a great PDRN serum as well. What they excel at is immediate glow. Of course consistency matters.…"
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"my skin soft, hydrated, and bouncy. For reference the serum and retinol are roughly the same price. I used Medicube pink serum (salmon) and I liked it but can tell the Iope does more for my skin. I’m over 40 btw."
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"using Numbuzing #9 Toner, Bio-Essence and Retinol Eye Cream (swapping the eye cream for something like Medicube's PDRN during the day) My moisturizers are constantly changing because although I've found many that I've…"
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"From medicube I have been using the pink serum for over a month, among other moisturizer and sheet mask, The improvement in my skin has shown improvement I don't know how to post pic, where I have the before and after"
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"Get the Medicube PDRN pink glow serum, Aestura AtoBarrier Cream, Biodance face mask.. and exfoliate with BHA toner twice a week 🤩"
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"Routine: AM L’Oréal revitalift glycolic acid cleanser Medicube Pink PDRN Toner Poor Reducing Pads BOJ Brightening Peptide Serum Burt’s Bees Skin Tightening Serum Corsx Snail Mucin Moisturizer BOJ Tinted SPF PM Medicub…"
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"Numbuzin 9 essence Medicube Pink PDRN serum Medicube collagen night wrapping mask These three gave me glass skin in 3 days!!!"
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"Numbuzin #9: Toner and Serum. Both products have multiple types of peptides plus NAD. I also use Medicube's PDRN Eye Cream and their PDRN Gel moisturizer. I've been very pleased with them all. No one suspects that I'l…"
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"definitely not good as a day cream,...but I think it makes a great overnight mask. Medicube just launched a PDRN+collagen jelly mist, is a spray so I got one but didn´t use it yet (too many products open in my counter…"
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"I just got the medicube pdrn mask from this place and I'm obsessed. It's literally the one thing I've ever used that actually makes my pores shrink. I'm about to order another box of them lol I went through the first …"
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"I'm currently doing a split face test with this and the medicube PDRN toner. I think I like the numbuzin side better, but its only been a couple of days."
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"I’m on my 2nd bottle of medicube PDRN pink peptide serum with no ill results. Maybe not a miracle treatment, but it feels good on my skin. I am moving on to Centrella24 active renew PDRN. I’ll admit I “clearly do t kn…"
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"will never buy Medicube again. When I ruin my skin barrier deliberately with dermarolling and/or the Medicube Pink Collagen Exosome Shot 7500, Medicube PDRN always helps me fix it quickly. I apply the Medicube PDRN to…"
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"with just 100 ppm, that’s 0.01%, compared to the medicube serum that has 10 000 ppm - 1 %, Heveblue, medicube, genabelle have high concentration of pdrn, i cannot speak of its anti aging benefits but pdrn has done won…"
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"pads - only at night. Will likely not rebuy as that's a lot of BHA/AHA and my BOJ was working fine. 4. Medicube pink pdrn milky toner - will probably get a different milky toner. My skin feels so nice though. (Buckle …"
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"in the comments. Skin type: Dry and sensitive Skin concerns: Hyperpigmentation, anti aging, acne prevention Medicube rose PDRN serum (4/10) Scent: Rose Texture: watery serum Product claims: anti aging, dryness, dullne…"
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"young will have some great sales coming up. My recommendations would be skin1004 centella cleansing foam, medicube pdrn toner, aestura essence and dr althea 147 barrier cream to "seal" everything in."
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"good quality - got the best nail clippers I have ever used and some fantastic brushes. They showed me the Medicube PDRN Pink Hyaluronic Moisturing cream which is popular in Korea atm. I also picked up some Rejuran mas…"
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"I personally love the Medicube PDRN night wrapping mask! I have combination skin (oily t zone, dry cheeks and congestion typically in my t zone) and it helps seal my products so they absorb all night. I wake up lookin…"
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"extra attention to your eyes / applying eye cream in general was probably what helped most. Because most Medicube “PDRN” products have a super small, basically negligible amount of actual PDRN. ie: the famous PDRN col…"
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"Medicube's pdrn line broke me tf out. I was so sad, but are you sure it's the snail mucin?"
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"That particular Medicube serum only has 1% PDRN (10,000 ppm) so it's not really effective."
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"Medicube's PDRN line is so good! I've been using the PDRN serum for some time now and it has done wonders to my skin:)"
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"Ato cream or Aestura 365 cream, and either BOJ sun relief SPF OR Skin1004 waterfit sun serum. As my PDRN serum I tried Medicube pink, Genabelle hyper booster and settled on Rejuran dual effect occasionally. I use as n…"
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"labels to be prettier than the very bold bright ones tho. I do find some of them seem gimmicky like the medicube capsule cream. Like, I find the packaging for the Heveblue salmon caring line to be very pretty most wou…"
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Threads tracked
The conversations we're watching.
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r/tretinoin
1 Year Of Tret 1 Year Of Taz
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r/KoreanBeauty
Routine And Product Help Please
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r/KoreanBeauty
Skin1004
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r/koreanskincare
r/koreanskincare
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r/koreanskincare
r/koreanskincare
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r/koreanskincare
Sometimes You Need To Listen The Majority And
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r/koreanskincare
r/koreanskincare
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r/koreanskincare
r/koreanskincare
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